Re: NONMEM $PRIOR related question
Hi Santosh,
If I understand your question, the THETA prior variance - covariance matrix
should provide variances for THETA priors. Therefore the upper limit of its
size should equal the number of THETAs with priors.
If the size is lower than number of THETAs with priors, then THETA priors
without specified variances become uninformative priors (i.e., large
variance is assumed).
Best.
Eliford
Quoted reply history
On Fri, Apr 5, 2024, 3:56 PM Santosh <[email protected]> wrote:
> Hi
>
> Not sure if my earlier post went through, hence re-posting …
>
> While running a model with $PRIOR in NONMEM, is there an upper limit on
> the size of variance-covariance matrix given as prior ? One of the
> examples (example6) in NONMEM documentation shows up to 8x8 matrix. I am
> currently using NONMEM version 7.3.0 or later.
>
> TIA
> Santosh
>