PAGE 2023 - Certara Satellite workshops 27th June

We have two workshops before PAGE that you may find interesting, they can easily be found here at our training site https://www.certarauniversity.com/store?utf8=%E2%9C%93&ss=1&ct=102967&commit=Filter Workshop: An Introduction to CAR-T Population Kinetic https://www.certarauniversity.com/store/3090941-workshop-an-introduction-to-car-t-population-kinetic-analysis 27th June 2023 8 AM-12 Facilitators: Mirjam Trame and Stephen Duffull This hands-on workshop will provide an introduction to CAR-T population kinetic analysis and CAR-T concepts including: * therapeutic utility and challenges in drug development of CAR-T initiatives * the basis for understanding the cellular kinetics of CAR-T cells * models that have been used to describe the kinetics of CAR-T cells and typical inferences * CAR-T cell kinetic modelling The workshop consists of lectures and interactive hands-on sessions using NONMEM and R. During the hands-on session participants will have the opportunity to explore CAR-T cell data and key features of cellular kinetics as well as fit base models to cellular kinetic data in order to understand the nuances of CAR-T cell kinetic modeling for autologous and allogenic CAR-T cell therapies. It is expected that participants will bring their own devices and have access to and familiarity with NONMEM and R. Tutorial: Effective Visualizations for Pharmacometric Models https://www.certarauniversity.com/store/3082574-tutorial-effective-visualizations-for-pharmacometric-models-vachette 27th June 2023 1:00 PM 5:00 PM Visualization of pharmacometrics models and data is often central to effectively informing drug discovery and development decisions. A previously published method (V2ACHERa) yielded an intuitive, clear visual overlay of data for certain GNLS, GLM, and NLME models, allowing an integrated display (in a single plot) of model predictions and data from different groups (i.e. across covariate-value-defined subgroups). This four-hour, hands-on tutorial will teach you how to use VACHETTEb, an improved and automated method enabling improved visualizations for PMX models with covariates, improving assessment and communication of model fit for both modelers and non-modelers. VACHETTE can also be applied to overlay data and models or for visual predictive checks (VPC), often yielding improved interpretability compared to traditional trellis plots, VPC, or pcVPC. The workshop will include lectures and hands-on exercises. Participants can also bring their own examples. The VACHETTE tutorial will use an open-source R package developed by Certara that will be freely available shortly. And you can access a special bundle pricing CAR-T workshop + VACHETTE visualization tutorial https://www.certarauniversity.com/store/4174-page-2023-car-t-workshop-vachette-visualization-tutorial-bundle?is_bundle=1 Simon DAVIS, Senior Support Scientist, Certara. This message (including any attachments) may contain confidential, proprietary, privileged and/or private information. The information is intended to be for the use of the individual or entity designated above. If you are not the intended recipient of this message, please notify the sender immediately, and delete the message and any attachments. Any disclosure, reproduction, distribution or other use of this message or any attachments by an individual or entity other than the intended recipient is prohibited.