Astrazeneca - Senior Scientist in PMx in Barcelona, Spain

Dear all - We are seeking an early career pharmacometrician for a growing group and site in Barcelona, Spain. If you or someone you know is interested please reach out to me, or apply at the link. Senior Scientist Clinical Pharmacology and Pharmacometrics (Pharmacometrician) https://careers.astrazeneca.com/job/barcelona/senior-scientist-clinical-pharmacology-and-pharmacometrics-pharmacometrician/7684/43318523936 Do you have expertise in, and passion for Pharmacology and Pharmacometrics? Would you like to apply your expertise to impact the lives of patients in a company that follows the science and turns ideas into life changing medicine. At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person. The Senior Scientist position is a scientific job with responsibility for pharmacometrics (PMx) activities including population PK, PKPD, exposure-response, and drug-disease modelling in all clinical development phases. With support from more senior Pharmacometricians, Team Leads and the TA Head, the incumbent will be responsible for integrating and analysing internal (and external) data to support interpretation and decision making. The individual will work to leverage foundational and cutting-edge pharmacometrics techniques, in combination with business domain knowledge, to develop and apply advanced models to generate business and scientific insights. The role will work within defined project scope and solutions aligned to established governance frameworks and policies. Responsibilities: * Accountable for data integration, analysis, and reporting of PMx results at the study level * Accountable for executing state-of-the-art PMx techniques with direct value for the project * Contribute PMx activities to influence study designs and go/no go decisions * Contribute to regulatory documents and interactions (written) * Presentation of PMx results in internal and external forum * Contribute to internal initiatives to develop the pharmacometric discipline including its processes * Participation in peer review of ongoing activities, reports and presentations * Compliance with Good Clinical Practice (GCP) regulations as well as internal/external guidance's Requirements: * Training and experience with pharmacometrics PK/PD software (NonMem, R, Stan, Monolix, or similar) * Demonstrated experiences in pharmacometrics, including PK, PKPD and/or statistics * Strong quantitative skills (e.g. experience in population modelling, statistics, systems and translational pharmacology modelling). * Ability to identify, develop and execute clinical pharmacometrics activities at a project level * Basic oral and written communication skills * Fluency in English (oral and written) * PhD degree preferred or equivalent (M.Sc./Pharm.D.) with relevant experience required Desirable: * Scientific publishing in the field on pharmacometrics * Early or late phase clinical development experience/awareness * Experience with concentration-QTc pharmacometrics analysis Why AstraZeneca? At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial -finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we're opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey. Best regards Chris Chris Penland, PhD Senior Group Director, Clinical Pharmacology & Pharmacometrics __________________________________________ AstraZeneca R&D | Clinical Pharmacology & Safety Sciences 35 Gatehouse Dr, Waltham, MA USA 02451 T: +1 781 839 4618 M: +1 617 275 3769 [email protected]<mailto:[email protected]> Please consider the environment before printing this e-mail ________________________________ Confidentiality Notice: This message is private and may contain confidential and proprietary information. If you have received this message in error, please notify us and remove it from your system and note that you must not copy, distribute or take any action in reliance on it. Any unauthorized use or disclosure of the contents of this message is not permitted and may be unlawful.