Re: Statistical power computation based on the wald test

Dear Hammami, Do you mean starting from a so-called full (pre-specified) model, and approximate which covariates in the nonmem model would reach statistical significance? See the publication by Kowalski: https://ascpt.onlinelibrary.wiley.com/doi/abs/10.1016/j.clpt.2003.11.158 https://ascpt.onlinelibrary.wiley.com/doi/abs/10.1016/j.clpt.2003.11.158 Best regards Jakob Jakob Ribbing, Ph.D. Senior Consultant, Pharmetheus AB Cell/Mobile: +46 (0)70 514 33 77 [email protected] www.pharmetheus.com Phone, Office: +46 (0)18 513 328 Uppsala Science Park, Dag Hammarskjölds väg 36B SE-752 37 Uppsala, Sweden This communication is confidential and is only intended for the use of the individual or entity to which it is directed. It may contain information that is privileged and exempt from disclosure under applicable law. If you are not the intended recipient please notify us immediately. Please do not copy it or disclose its contents to any other person.