WCoP Workshop: Open Source Pharmacometrics Open for registration

An open-source Pharmacometrics’s workflow in R: from exploration (xGx) to model building (nlmixr) and diagnostics (ggPMX) Sponsored by Novartis and co-hosted by Pharmacometrics Africa https://www.pmxafrica.org/, NPC Workshop target audience: Pharmacometricians/modelers with basic knowledge on model building, evaluation and qualification. Basic knowledge of writing, executing R scripts is advantageous. Workshop faculty: Fariba Khanshan, Novartis Pharmacometrics, Cambridge, USA Matt Fidler, Novartis Pharmacometrics, Fort Worth, USA Irina Baltcheva, Novartis Pharmacometrics, Basel, Switzerland Overview: The workshop will provide a tutorial on three open–source R packages currently under development at Novartis, supporting the pharmacometrics workflow in exploring and modelling clinical data: - Exploration of the data using the Exploratory Graphics (xGx) package, available on GitHub ( https://opensource.nibr.com/xgx/). - Population PK and PKPD modelling of the data using nlmixr ( www.nlmixr.org http://github.com/nlmixrdevelopment/nlmixr). nlmixr builds on the ODE solving in the RxODE package, by implementing parameter estimation algorithms like nlme, SAEM and FOCE with interaction. - Model building and validation using ggPMX, a library of reproducible diagnostic plots available on CRAN and on Github (https https://github.com/ggPMXdevelopment/ggPMX:// https://github.com/ggPMXdevelopment/ggPMX github.com/ggPMXdevelopment/ggPMX). The combination of the three open-source R packages provides the pharmacometrics modelling community the opportunity to reduce the learning curve needed to become proficient on each of the different tasks using a stepwise framework. Fees: $25 / R400 Click here for more info https://wcop2020.org/wp-content/uploads/2020/01/An-open-source-Pharmacometricians-workflow-in-R-Novartis.pdf Click here to register https://allevents.eventsair.com/wcop2020/workshop