Re: FDATA file bug

On 2019-12-05 08:23, Mark Tepeck wrote: > Hi Nordgren and Denny, > > Thanks for your tips. Here are the NONMEM script, input CSV file row 1, and FDATA row 1. I also attached the original model file, CSV input file as well as the FDATA (not sure NMuser allows attachment) for troubleshooting. I did observe that multiple columns from input were combined to fewer columns in the FDATA file. I also found occasional generation of *fdata-1* file but not sure its role. > > * > * > *The input CSV file (17 columns) * > > CID, TIME, CONC, AMT, DOSE, MDV, AGE, WT, SCR, ISM, CLCR, AA, BB, CC , DD, EE, FF 1, 0 , 0, 100, 100, 1, 34.823, 38.212, 1.1129, 0 , 42.635, 42.635, 42.635, 42.635, 42.635, 42.635, 42.635 > > *FDATA (6 columns):* 1, 0, 0100100134.82338.212, 1.1129042.63542.63542.63542.63542.635, 42.63542.635,1 > > *NONMEM script:* > > $PROBLEM Test Fdata > $DATA CS1_IV1EST_PAR.CSV IGNORE=C > $INPUT ID TIME DV AMT DOSE MDV AGE WT SCR ISM CLCR AA BB CC DD EE FF > $SUBROUTINE ADVAN1 TRANS2 > $PK > CL = THETA(1)*EXP(ETA(1)) > V= THETA(2)*EXP(ETA(2)) > S1 = V > > $ERROR > IPRED = F > Y=F+F*ERR(1)+ERR(2) > > $THETA > (0.1,1) > (1,10,20) > $OMEGA > 0.09 > 0.09 > $SIGMA > 0.09 > 1 > $ESTIMATION METH=1 MAXEVAL=9999 PRINT=5 POSTHOC > $TABLE ID TIME DV FILE=CS1_IV1ESTFPDF.fit > > I really appreciate your input. > > Mark > > On Tue, Dec 3, 2019 at 11:57 PM Rikard Nordgren < [email protected] < mailto: [email protected] >> wrote: > > Hi, > > NM-TRAN will not add columns not listed in $INPUT or > dropped/skipped to FDATA. Could that be the reason? > > Best regards > Rikard Nordgren > > On 2019-12-04 01:27, Mark Tepeck wrote: > > > Hi All, > > > > I am using NONMEM 7.4.3. I want to confirm the right input > > dataset into NONMEM. However, I found that the FDATA file can > > save only around the beginning 9 columns of the original CSV > > file. The ending columns (e.g., column 10-20) are either missing > > or combined into a single column in the FDATA file. > > > > I am not sure other people encountered the same problem. > > > > Thank you, > > > > Mark > > -- Rikard Nordgren > > Systems developer > > Dept of Pharmaceutical Biosciences > Faculty of Pharmacy > Uppsala University > Box 591 > 75124 Uppsala > > Phone: +46 18 4714308 > www.farmbio.uu.se/research/researchgroups/pharmacometrics/ > http://www.farmbio.uu.se/research/researchgroups/pharmacometrics/ > > När du har kontakt med oss på Uppsala universitet med e-post så > innebär det att vi behandlar dina personuppgifter. För att läsa > mer om hur vi gör det kan du läsa här: > http://www.uu.se/om-uu/dataskydd-personuppgifter/ > > E-mailing Uppsala University means that we will process your > personal data. For more information on how this is performed, > please read here: http://www.uu.se/en/about-uu/data-protection-policy -- Rikard Nordgren Systems developer Dept of Pharmaceutical Biosciences Faculty of Pharmacy Uppsala University Box 591 75124 Uppsala Phone: +46 18 4714308 www.farmbio.uu.se/research/researchgroups/pharmacometrics/