WCoP 2020 Workshop: Modeling Delays in NONMEM

The Pharmacodynamic Systems with Delays Research Group will present a one day workshop on Modeling Delays in Pharmacokinetics and Pharmacodynamics using NONMEM on Sunday April 5 2020 at WCoP 2020 in Cape Town, South Africa. The course will provide an overview of biological systems exhibiting delays, concepts of lifespan driven pharmacodynamic response, modeling of cell maturation, transduction delays, and nonlinear mixed effect lifespan models. Delay differential equations (DDEs) will be introduced and implemented in NONMEM pre-release version 7.5. The course will consist of both lectures and hands-on computer exercises. Source code for DDE based PK/PD models and data will be provided to the participants. For more information and registration: https://sites.google.com/site/delaysinpkpd or contact wk (at) buffalo.edu. Best Gilbert Koch