Quantitative Clinical Pharmacology Position at GSK

We have an exciting opportunity at GlaxoSmithKline (GSK) for a highly motivated Quantitative Clinical Pharmacologist to join our London team as part of the global department of Clinical Pharmacology Modelling & Simulation. This is an excellent role to use quantitative clinical pharmacology to accelerate the delivery of new medicines to patients by enhancing drug program efficiency and business decision quality. The work directly supports our mission to help our patients do more, feel better and live longer. Responsibilities will include: 1. Plan, execute and report translational drug-disease modelling, exposure-response analysis, simulation-based trial design and population clinical pharmacology * 2. Contribute to clinical program design, trial protocols, analysis plans, study reports and regulatory submissions * 3. Apply innovative techniques such as longitudinal exposure-response analysis, model-based meta-analysis and item-response analysis to improve data use and trial efficiency * 4. Present strategy and discuss outcome of model-based approaches via interactions with internal governance boards and regulatory agencies * 5. Promote model-informed drug discovery and development through external collaboration, journal publication and conference presentation Qualification requirements: 1. A doctorate relevant to Quantitative Clinical Pharmacology, and experience in using modelling/simulation to solve practical problems in industry or academia 2. Proven skills in pharmacokinetic-pharmacodynamic and longitudinal disease modelling; and verifiable proficiency in pharmacometric tools NONMEM, Monolix, R or SAS 3. Strong drive and learning agility to build knowledge on a drug-disease system, symptom progression, standard of care, and trial design and endpoints 4. Demonstrated aptitude for productive collaboration in a multi-discipline team, using effective communication and taking personal accountability for timely delivery of results 5. Clear evidence of ability to make sound judgement in complex situations and adapt to changing business needs by prioritising multiple tasks The job level will depend on the skills and achievements of the successful candidate. At GSK, we develop therapies of various modalities for a broad range of indications. As a member of a global department with diverse expertise, you will enjoy a highly supportive environment for scientific innovation, business impact and professional growth. This position is open for application till Wednesday 5th August 2019. Interested persons are encouraged to apply online https://careers.peopleclick.com/careerscp/client_gsk/external1931/gateway.do?functionName=viewFromLink&jobPostId=410854&localeCode=en-us. Chao Chen Clinical Pharmacology Modelling & Simulation GlaxoSmithKline R&D GSK monitors email communications sent to and from GSK in order to protect GSK, our employees, customers, suppliers and business partners, from cyber threats and loss of GSK Information. GSK monitoring is conducted with appropriate confidentiality controls and in accordance with local laws and after appropriate consultation. ________________________________ This e-mail was sent by GlaxoSmithKline Services Unlimited (registered in England and Wales No. 1047315), which is a member of the GlaxoSmithKline group of companies. The registered address of GlaxoSmithKline Services Unlimited is 980 Great West Road, Brentford, Middlesex TW8 9GS.