Career Opportunity - PK/PD Scientist, Biologics Development Sciences, Janssen R&D
*Dear NMusers community,*
Janssen Research & Development, a Johnson & Johnson Company is recruiting
for a *PK/PD Scientist, Biologics Development Sciences (BDS), Janssen
BioTherapeutics (JBIO) to be located in Spring House, Pennsylvania.*
At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are
working to create a world without disease. Transforming lives by finding
new and better ways to prevent, intercept, treat and cure disease inspires
us. We bring together the best minds and pursue the most promising science.
We are Janssen. We collaborate with the world for the health of everyone in
it. Learn more at www.janssen.com and follow us _at_JanssenGlobal. Janssen
Research & Development, LLC is part of the Janssen Pharmaceutical Companies.
The PK/PD Scientist primarily supports discovery, preclinical and early
clinical development of therapeutic biologics across all Therapeutic Areas.
As a key player of the BDS team, the position will address critical ADME,
PK and PK/PD related questions to enable time-appropriate decision-making
for early stage biologic programs. The responsibilities of this position
also include lead and active participation in pertinent JBIO Teams (JBTs),
Compound Development Teams (CDTs) and other project teams across all phases
of drug research and development.
The scope of this exciting position encompasses:
- Development of mechanism-based modeling and simulation and apply them
into target evaluation, biologics drug design, candidate selection and
therapeutic index projection
- Drive for innovation by identifying critical knowledge gaps, e.g.
explore PK/PD relationship for novel biotherapeutics such as cell therapy
or gene therapy, and leveraging internal/external expertise to address
these gaps
- Representation of BDS in cross-functional project teams for biologics
across therapeutic areas
- Responsible for First-in-Human starting dose selection and efficacious
dose prediction
- Contribution to relevant sections of internal and regulatory
submission documents for biologics
- Presenting and publishing scientific data at conferences and in
peer-reviewed journals
*Qualifications*
- A PhD or PharmD in Pharmaceutical Sciences, Clinical Pharmacology, or
Biological Sciences OR a PhD or PharmD expected within 6 months in
Pharmaceutical Sciences, Clinical Pharmacology, or Biological Sciences OR a
MS in Pharmaceutical Sciences, Clinical Pharmacology, or Biological
Sciences with at least 5 years of experience is required. *More senior
title can be considered for highly-qualified candidates with more
experience.*
- Extensive experience with quantitative approach in describing PK/PD
systems using preclinical and/or clinical data and demonstrated ability to
apply quantitative tools to enable rational and efficient drug development
are required.
- Proficiency in WinNonlin/Phoenix is preferred; NONMEM and/or other
advanced modeling and simulation software (e.g. Monolix, Matlab, etc.) is
required
- Broad experience in mechanism-based PK/PD research of biologic
therapeutics and/or small molecule therapeutics is strongly preferred
- Experience in biologics and/or small molecules drug development is
preferred.
- A strong publication record is highly preferred.
Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer.
All qualified applicants will receive consideration for employment without
regard to race, color, religion, sex, sexual orientation, gender identity,
age, national origin, or protected veteran status and will not be
discriminated against on the basis of disability.
*Interested candidates kindly email your CVs to szheng13_at_its.jnj.com
<szheng13_at_its.jnj.com> *
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