Re: current sigma

On 2018/11/08 5:10, Bauer, Robert wrote: > Try the following examples, according to your need, in $PRED or $PK: > > SIGVAL11=SIGMA(1,1) > OVAL22=OMEGA(2,2) > > IF(NEWIND.eq.0) WRITE(*,*) SIGVAL11,OVAL22 > ... > $TABLE SIGVAL11 OVAL22 > > Robert J. Bauer, Ph.D. > Senior Director > Pharmacometrics R&D > ICON Early Phase > 820 W. Diamond Avenue > Suite 100 > Gaithersburg, MD 20878 > Office: (215) 616-6428 > Mobile: (925) 286-0769 > [email protected] <mailto:[email protected]> > www.iconplc.com http://www.iconplc.com > > -----Original Message----- > > From: [email protected] < mailto: [email protected] > [ mailto: [email protected] ] On Behalf Of [email protected] < mailto: [email protected] > > > Sent: Sunday, November 04, 2018 7:03 PM > To: [email protected] <mailto:[email protected]> > Subject: [NMusers] current sigma > > Hello, > > I would like to know how to know current sigma values in a customized PRED > > routine. In noncom.for file, it is documented that initial and final theta, omega and sigma values are set in ROCM6, and current omega values are set in > > ROCM22. However, I cannot find current sigma values. > > We developed a new program which can restore numerous time-course data by > expanding the analysis of nonlinear mixed effect model. Detail of our > analysis, named SReFT, is described in recent Clin Pharm Ther > (PMID:29951994). Currently, SReFT is implemented in my own program, Napp, > > but I am considering its implementation in NONMEM. For the implementation of > > SReFT, it is necessary to know current sigma value in the PRED routine. > > Akihiro Hisaka, > Chiba University, Japan. > email: [email protected] <mailto:[email protected]> > >