RE: R for regulatory use

From: Ruben Faelens Date: March 23, 2018 technical Source: mail-archive.com
Dear Christina, I would love to learn a bit more about this, and an open discussion on this list is probably the best way. Could you elaborate how specifically the open source nature of R causes concern? See the nice documentation from the R project core team at https://www.r-project.org/doc/R-FDA.pdf It seems to me that solid controls are in place, and the self-evaluation of 21 CFR part 11 by the R Core team does not result in any cause for concern. Perhaps I misinterpret or am too optimistic: Which parts of this self-evaluation document would you consider insufficient, or cause for concern? Also see https://www.r-bloggers.com/r-drug-development-and-the-fda/, https://www.r-bloggers.com/fda-r-ok-for-drug-trials/, and especially presentations/posters from people at FDA: http://user2007.org/program/presentations/soukup.pdf and http://blog.revolutionanalytics.com/downloads/FDA-Janice-Brodsky-UseR-2012.pdf I am quite allergic to people sowing fear, uncertainty and doubt on open-source software, especially when commercial off-the-shelf software is held to different standards. Best regards, Ruben Faelens
Quoted reply history
From: [email protected] [mailto:[email protected]] On Behalf Of Christina Halliday Sent: vrijdag 23 maart 2018 15:32 To: [email protected] Subject: [NMusers] R for regulatory use Hi Everyone As we know R has become the programming language of choice in many industries due to its cutting edge capabilities. However, R's open source nature can cause concern for heavily regulated industries and companies that have strict policies around open source usage. To overcome these concerns, Mango developed "ValidR". Mango's dedicated Validation team have been supporting ValidR customers for a number of years. ValidR delivers a controlled and validated version of open source R in line with regulatory guidelines such as FDA 21 CFR part 11. To find out more about ValidR, join our 30-minute free public webinar on Thursday 19 April. Register for your place here: https://www.mango-solutions.com/validr/ Any questions please feel free to contact us at [email protected]<mailto:[email protected]> Kind regards Christina -- LEGAL NOTICE This message is intended for the use of the named recipient(s) only and may contain confidential and / or privileged information. If you are not the intended recipient, please contact the sender and delete this message. Any unauthorised use of the information contained in this message is prohibited. Mango Business Solutions Limited is registered in England under No. 4560258 with its registered office at Suite 3, Middlesex House, Rutherford Close, Stevenage, Herts, SG1 2EF, UK. PLEASE CONSIDER THE ENVIRONMENT BEFORE PRINTING THIS EMAIL Information in this email and any attachments is confidential and intended solely for the use of the individual(s) to whom it is addressed or otherwise directed. Please note that any views or opinions presented in this email are solely those of the author and do not necessarily represent those of the Company. Finally, the recipient should check this email and any attachments for the presence of viruses. The Company accepts no liability for any damage caused by any virus transmitted by this email. All SGS services are rendered in accordance with the applicable SGS conditions of service available on request and accessible at http://www.sgs.com/en/Terms-and-Conditions.aspx
Mar 23, 2018 Christina Halliday R for regulatory use
Mar 23, 2018 Ruben Faelens RE: R for regulatory use
Mar 23, 2018 Edward Gash RE: R for regulatory use
Mar 23, 2018 Chris Penland RE: R for regulatory use