Inherit past calculation of parameter in NONMEM
Dear NMusers,
Maybe a simple question. I was wondering if there is such functionality in
NONMEM to inherit the past (e.g. previous row) value of parameter calculated
with time varying covariates? For instance, the CL was determined by a time
varying covariate. Calculation CL was a negative number in time record 3 due to
the covariate value at that time point. I would like to use calculation CL in
time record 2 as instead for time record 3. Pseudocode is somewhat like 'IF
(CL[i].LE.0) CL[i]=CL[i-1]'. Is this possible to implement within NONMEM?
Thanks in advance.
Warm regards,
Tingjie
Tingjie Guo I Trainee Research Assistant
Academic Medical Centre, University of Amsterdam.
VU University Medical Centre, Vrije University Amsterdam.
Room ZH-7D-172, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
Email: [email protected]<mailto:[email protected]> /
[email protected]<mailto:[email protected]> Mobile: +31 659738693