RE: $Error log transformed
Hi Katrin,
You'll have to take the natural logarithm of your DVs
I would change your error block to:
$ERROR
IPRED=LOG(F+1E-16) ; Protection against LOG(0) in case of dosing events etc
Y=IPRED+ERR(1) ; FOR PROPORTIAL ERROR
Cheers!
Rob
Quoted reply history
Van: [email protected] [mailto:[email protected]] Namens
Katrin Volz
Verzonden: vrijdag 16 december 2016 10:35
Aan: [email protected]
Onderwerp: [NMusers] $Error log transformed
Dear All,
I would like to model my data log transformed.
So far, I already found some suggestions for this problem here but none of them
worked in my case - probably I did sth. wrong.
I would be very happy if someone could help me with changing my error model,
which I assume has to be changed.
(I also assume that the dataset has to be changed from DV to LOG(DV)?)
So, here is the code I used so far (not log transformed):
$ERROR
IPRED = F ;IPRED drug in the
central compartment
IF (CMT.EQ.5) IPRED = A(5) ;IPRED second drug in 5th compartment
DEL=0
IF (IPRED.EQ.0) DEL=0.0001
W = F
IRES = DV - IPRED
IWRES = IRES /(W + DEL)
Y = IPRED + IPRED * EPS(1) ; error drug in the
central compartment
IF (CMT.EQ.5) Y = IPRED + IPRED * EPS(2) ; error second drug in 5th
compartment
It would be great to get some help.
Thanks!
Katrin
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