Additional predicted levels (EVID=2) changed objective function values

From: Zheng Liu Date: February 15, 2016 technical Source: cognigen.com
Dear NMusers, I intended to print out more predicted levels at the time points without observations. Therefore I inserted those lines with EVID=2 in the data set. Surprisingly after doing so, the objective function value and the fitted parameter values changed more or less. This should not be rational. Could anyone explain the reason and how to avoid it? Thanks a lot in advance! Best regards? ? Zheng Liu, Ph.D. Pharmacometrician (postdoc), Melbourne Royal Children's Hospital email: Zheng.Liu_at_rch.org.au