Re: Incorporating standard deviation (SD) on fitted mean values

On 11/19/2015 9:58, Nick Holford wrote: > Some of the RUV arises from within study between subject variability > in A and ALPHA and some from the usual sort of RUV (model > misspecification, measurement error, stochastic noise, etc) Agree. In this case, I don't think it matters where the variability comes from. It's part of the data, with each reported outcome defined by c(mean,sd). sd incorporates both between- and within-subject variability. Separating BSV and WSV is tricky when only aggregate data is available. -- Paul Matthias Diderichsen, PhD Quantitative Solutions, a Certara company +31 624 330 706