Question of fitting population PK model using summary statistics of data instead of raw data

From: Penny Zhu Date: September 10, 2015 technical Source: mail-archive.com
Dear all Assuming the population PK or PD data are log-normally (or normally) distributed, if you have the mean and standard deviation of a readout at each timepoint but do not have the actual raw data (assuming all pateints are with the same dosing regimen, etc), is it possible to establish a well fitted population PK or PD model? How would one get about doing it? Your help is very much appreciated Penny