Quantitative Pharmacology Positions @ Merck Serono

Merck is a global leader in specialized pharma and chemicals, and for almost 350 years we have improved people's quality of life. This is due to the creativity and team spirit of our 40,000 employees around the world, so we're committed to help them develop and to reward their excellence. PHARMACOMETRICIAN POSITIONS @ Merck Serono The Quantitative Pharmacology department at Merck Serono gathers under the same roof modelers with broad expertise from translational PKPD to PBPK, and up to pharmacometrics. We work on projects covering small molecules, large molecules modalities and more recently ADCs, all the way in the drug development value chain from early Discovery up to Life Cycle Management, with exciting programs in (Immuno-) Oncology and (Auto-) Immune Diseases. Our group is expanding and we have several open opportunities in in Frankfurt area/Germany and in Lausanne/Switzerland. WHO YOU ARE: You are an enthusiastic, strong team player, reliable, dedicated, competent professional seeking opportunities to develop and grow in a dynamic environment and recognized group? Go to https://career012.successfactors.eu/career?company=merckgroup and enter the Req ID that interests you: * Team Leader, Pharmacometry, Frankfurt area, Germany (Req ID: 41221) * Senior Scientist, Pharmacometry, Frankfurt area, Germany (Req ID: 88561) * Senior Scientist, Pharmacometry, Lausanne, Switzerland (Req ID: 59283) * Postdoc Pharmacometry (1.5 Y contract), Lausanne, Switzerland (Req ID: 86766) PROFESSIONAL SKILLS & EXPERIENCE SPECIFIC FOR THE TEAM LEADER POSITION * Being an established senior scientist * 5 to 7+ years experience in PKPD Modeling, of which 3+ in BioPharmaceutical Industry. * Having successfully run pharmacometric project in drug development and/or having some experience of management over a small team of pharmacometry. * Experience with PKPD M&S input into drug development. PROFESSIONAL SKILLS & EXPERIENCE FOR ALL POSITIONS * Good command of NONMEM is an absolute prerequisite, experience with MONOLIX is an asset. * Good command of R is an absolute prerequisite, experience with SAS is an asset. * Experience with PsN and Xpose is another asset. * Experience with Clinical Trial Simulation tools is another asset, alike for other analytical/modeling/ optimization/presentation software or language, e.g. ADAPT, SAAM II, BERKELEY MADONA, SIMCYP * Experience in writing and using PKPD models, particularly mechanistic-models and in developing disease progression models is an asset. * Overall good knowledge of common PC software. PERSONAL SKILLS & COMPETENCIES * Strong problem solving skills and ability to analyze complex problems * Has interest in, and knowledge of, both mathematical and (patho-)physiological aspects of M&S in drug development * Is enthusiastic, self-motivated and has good communication skills, and at ease in working in a dynamic matrix organization; is a team-player. Communicate technical details effectively with scientists and clinicians colleagues With best regards , Pascal Girard Director, Pharmacometry Merck Serono | Global Early Development "Merck - Living Innovation" Merck Institute for Pharmacometrics - Merck Serono S.A. EPFL Innovation Park - Building I, CH-1015 Lausanne, Switzerland Phone: +41 21 900 3702 | Mobile: +41 79 508 7898 Email: [email protected] | www.merckserono.com Mandatory information can be found at: http://www.merckgroup.com/mandatories Please consider your environmental responsibility before printing this e-mail This message and any attachment are confidential and may be privileged or otherwise protected from disclosure. If you are not the intended recipient, you must not copy this message or attachment or disclose the contents to any other person. If you have received this transmission in error, please notify the sender immediately and delete the message and any attachment from your system. Merck KGaA, Darmstadt, Germany and any of its subsidiaries do not accept liability for any omissions or errors in this message which may arise as a result of E-Mail-transmission or for damages resulting from any unauthorized changes of the content of this message and any attachment thereto. Merck KGaA, Darmstadt, Germany and any of its subsidiaries do not guarantee that this message is free of viruses and does not accept liability for any damages caused by any virus transmitted therewith. Click http://www.merckgroup.com/disclaimer to access the German, French, Spanish and Portuguese versions of this disclaimer.