Implementation of NM to analyze in-vitro data on drug synergy
Dear NMUSERS,
I was wondering if anyone on this list has experience implementing analysis of
in-vitro data on drug synergy (combination of two anticancer drugs in different
concentrations) with the help of NONMEM, e.g. by the method of Chou and Talalay
(Cancer Research 70: 440-446 (2010)) or any other method and perhaps is willing
to share a control stream for inspiration?
Cheers,
Rob
R. ter Heine, PhD, PharmD
Hospital Pharmacist / Clinical Pharmacologist
Meander Medical Center, Amersfoort, The Netherlands
T: +31-33-8502335
E: [email protected]<mailto:[email protected]>
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