Register now open for the Optimal Design for Pharmacometrics Course February 9-12 2015, Munich, Germany

Optimal Design for Pharmacometrics 9 - 12 February 2015 Munich, Germany How do we use prior study information to improve the next study? Optimal Design does exactly this. We can predict better sampling times, better dose levels to use, the number of groups and subjects to use to achieve needed power, and more. Three of the world's top experts, Stephen Duffull, Andrew Hooker and France Mentré, in Optimal Design have created a customized four-day course to explain some of the theory behind Optimal Design, lead small group discussions on setting up, and interpreting Optimal Designs. An entire day will be devoted to hands-on examples with the PFIMOpt software. Prerequisites: Understanding of the basics of mixed effects compartmental modeling (aka, population modeling) and experience with some kind of population PKPD modeling software. Topics Include: · Introduction to the study design · Introduction to the Fisher Information Matrix (FIM) - FIM for nonlinear models and nonlinear mixed effects models - Design optimization - D-optimality, C-optimality, etc. and their interpretations · Accounting uncertainty in beliefs about the parameter and model space · Design constraints in optimization (number of samples, time ranges, groups, etc.) · Multiple response models - turnover models and others in PKPD · Maximizing the probability of experimental success, the ability to discriminate between models · An introduction to adaptive design · Handling data below the limit of quantitation · Study power and optimal design Sign up today! 20% early registration discount (Expires 8 December 2014) 30% off of groups 50% off for students Register Now. https://www.certara.com/training/classes/74 Special Rates Available at the Maritim http://www.maritim.de/de/hotels/deutschland/hotel-muenchen/uebersicht, http://www.maritim.de/de/hotels/deutschland/hotel-muenchen/uebersicht, if reserved by 14 December 2014 Please provide the code 1CER080215 Alicia Holmes Sales Support Specialist Certara(tm) Implementing Translational Science 210 N. Tucker Blvd., Suite 350, St. Louis, MO 63101 Tel 314-951-3012 Fax 314-951-3099 Certara: The name behind the names you know Tripos - Simcyp - Pharsight http://www.certara.com/