Workshop on Modeling Delays in Pharmacokinetics and Pharmacodynamics

A one day workshop on Modeling Delays in Pharmacokinetics and Pharmacodynamics will be presented by Wojciech Krzyzanski and Gilbert Koch (both University at Buffalo), Juan Jose Pérez-Ruixo and Sameer Doshi (both Amgen Inc.), Johannes Schropp (University of Konstanz), and Jérome Kalifa (Lixoft Inc.) on Tuesday 10th of June 2014. The course will provide an overview of biological systems exhibiting delays, concepts of lifespan driven pharmacodynamic response, modeling of cell maturation, and nonlinear mixed effect lifespan models. Delay differential equations (DDEs) will be introduced and implemented in PK/PD software such as NONMEM and Monolix. The course will consist of both lectures and hands-on computer exercises built in Berkeley Madonna. Source codes for DDE based PK/PD models will be provided to the participants. Contact [email protected]<mailto:[email protected]> for more information. For details about agenda and registration click http://www.page-meeting.org/../page/page2014/DDE-Workshop-PAGE-2014-final.pdf.