RE: Issues with NONMEM 7.2/MPI
Hi Katya,
I just tested your suggested solution and it works. I think for now we will
increase the timeout from 10 to 100 and keep monitoring how that goes with our
jobs.
BTW: The timeout only seems to occur when we use the same control stream with
10 cores. When using 20 cores, no timeout can be seen even when TIMEOUT=10 is
set. In this case I assume the workload is better distributed although total
compute time is only reduced by 35 % instead of 50 % one would expect for
"ideal" parallelization efficiency.
Many thanks for your help.
Michael.
Quoted reply history
From: Ekaterina Gibiansky [mailto:[email protected]]
Sent: Montag, 4. November 2013 16:47
To: Mayer, Michael; [email protected]
Subject: Re: [NMusers] Issues with NONMEM 7.2/MPI
Hi Michael,
We had this happening, and following conversation with Bob Bauer increased
TIMEOUT. According to him:
"TIMEOUT=10 means it waits up to 10 minutes for a worker to finish its
part of the OBJ function call. You seem to have a very tough job, so
set the TIMEOUT to something bigger. It does not hurt to set TIMEOUT to
1000000 or something really big. There is no inefficiency from it. The
manager continues polling the worker until the worker says it is done,
anyway. It does mean that if there was some difficulty with a worker
computer, and your TIMEOUT is very long, then the manager waits a very
long time before it decides to reroute the work."
Regards,
Katya
Ekaterina Gibiansky, Ph.D.
CEO&CSO, QuantPharm LLC
Web: http://www.quantpharm.com
Email: EGibiansky at quantpharm.com
Tel: (301)-717-7032
On 11/4/2013 4:10 AM, Mayer, Michael wrote:
Hi all,
just wondering if anyone of you has seen an issue like that.
Occasionally when we run parallel nonmem 7.2 jobs, we receive messages in
stdout similar to the ones highlighted in yellow below:
iteration 9 OBJ= -905.810529070325 eff.= 1198. Smpl.= 3000.
Fit.= 0.99553
Elapsed estimation time in seconds: 399.70
Last iteration, set up for variance assessment
TIMEOUT FROM WORKER5
RESUBMITTING JOB TO LOCAL
iteration 10 OBJ= -905.807559328067 eff.= 1216. Smpl.= 3000.
Fit.= 0.99559
OPTIMIZATION NOT TESTED
Elapsed covariance time in seconds: 1306.23
The nonmem run seems to be finished but the MPI processes keep spinning and the
non-interactive job never gets terminated. The only correlation to this
behavior we found so far was the appearance of the above error message.
We are using "PARSE_TYPE=4 PARSE_NUM=20 TIMEOUTI=100 TIMEOUT=10" in the pnm
file.
Has anyone seen the above behavior ? My original guess was that this would
occur if one of the nodes would crash and then NONMEM cannot communicate to the
MPI threads running on that node. In the case above all 10 threads were running
on the same node. The other guess was that one thread would take longer than
the TIMEOUT value (10 mins) but any thread was shorter than 3 mins.
Our system: RHEL5, mpich2-1.4.1p1, Intel Fortran 11.
Many thanks for any insight.
Michael.