Program details: 3rd Annual Indiana CTSI Symposium on Disease and Therapeutic Response Modeling

Just a reminder – if you haven’t already registered for our Third Annual Clinical and Translational Sciences Institute (CTSI) Symposium on Disease and Therapeutic Response Modeling to be held in Indianapolis, Indiana on November 5th and 6th, now is the time! The registration links are below. Our Poster Session / Cocktail Reception will be held on Tuesday evening from 5:30 – 7:00. More information can be found below. The program schedule can be found at the bottom of this email. The Third Annual Indiana Clinical and Translational Sciences Institute (CTSI) Symposium on Disease and Therapeutic Response Modeling November 5 and 6, 2013 We are pleased to announce that the third annual Indiana Clinical and Translational Sciences Institute (CTSI) Symposium on Disease and Therapeutic Response Modeling will take place on November 5-6, 2013 in Indianapolis, Indiana. This two-day program will include speakers from academia, industry and regulatory agencies, as well as poster presentations. The confirmed speakers include – Dr. Vikram Sinha (FDA), Dr. Jeffrey Barrett (Children's Hospital of Philadelphia), Dr. Marc Gastonguay (Metrum Institute), Dr. John Urquhart (AARDEX Group), Dr. Mark Sale (Next Level Solutions, LLC), Dr. Sean Mooney (Buck Institute for Age Research), Dr. Michael Heathman (Eli Lilly and Company), and Dr. Bernard Vrijens (MeadWestvaco Healthcare). REGISTRATION Link to registration: Academic, Government and Eli Lilly Company Free Symposium http://operations.medicine.iu.edu/index.php?cID=163 Industry $200 Paid Symposium https://indianauniv.ungerboeck.com/prod/SignIn.aspx?ReturnUrl=%2fprod%2femc00%2fregister.aspx%3fOrgCode%3d10%26EvtID%3d5870%26AppCode%3dREG&OrgCode=10&EvtID=5870&DictSeq=27&Lang=*&SessionID=ejofbkfe6ffofb5fc9&CultureInfo=en-US&AppCode=REG CONFERENCE LOCATION: Campus Center 420 University Blvd. CE 278 Indianapolis, IN, 46202 Phone: (317) 274-5555 POSTER SESSION: Poster Session / Cocktail Reception will be held on November 5th from 5:30 – 7:00 pm. If you are interested in submitting a poster for this session, please contact us no later than October 25, 2013. For more information or questions, please contact Shripad Chitnis ([email protected]<mailto:[email protected]>) or Nieves Velez de Mendizabal ([email protected]<mailto:[email protected]>) We look forward to seeing you in November! PROGRAM DETAILS: Tuesday, November 5, 2013 8:00 AM: Breakfast / Registration (30 min) 8:30 AM: Welcoming Remarks: Anantha Shekhar, M.D., Ph.D., Associate Dean for Translational Research, Professor of Pharmacology and Neurobiology, Indiana University School of Medicine 8:45 AM: Welcoming Remarks: Robert Bies, Ph.D., Director of the Disease Modeling Program for the Clinical and Translational Sciences Institute (CTSI), Indiana University School of Medicine 8:50 AM: Keynote Address: Vikram Sinha, Ph.D., Office of Clinical Pharmacology, Translational Sciences, FDA. 9:30 AM: Eric Meslin, Ph.D., Center for Bioethics at Indiana University School of Medicine “Traversing the Science Policy Valley of Death as a Strategy for Accelerating Translational Science” 10:10 AM: Coffee Break (20 min) 10:30 AM: Mark Sale, M.D., Next Level Solutions, LLC “Open Source NLME in Julia - Opportunity and Request for Wishlists” 11:10 AM: Marc Gastonguay, Ph.D., Metrum Research Group LLC TBA 11:50 AM: Sorell Schwartz, Ph.D., Dept. of Pharmacology and Physiology, Georgetown University Medical Center; Center for Biologics Evaluation and Research, Office of Biostatistics and Epidemiology, FDA “Is There a Need or Role for Preclinical Safety Assessment of Systemic Mesenchymal Stem Cell Therapy? Agent Based Modeling Applications” 12:30 PM: Klaus Romero, MD., Critical Path Institute “A Comprehensive Clinical Trial Simulation Tool for Alzheimer’s Disease: Lessons for Model Collaboration” 1:00 PM: Lunch (1 hr 15 min) 2:15 PM: Michael Brier, Ph.D., Department of Medicine, Division of Nephrology, University of Louisville “Model Predictive Control Applied to Therapeutic Drug Monitoring” 2:55 PM: Jeff Barrett, Ph.D., The Children's Hospital of http://www.linkedin.com/company/166358?trk=prof-0-ovw-curr_pos "Design, Governance and Implementation of a Web-Enabled Decision Support Tool to Manage High-Dose Methotrexate Pharmacotherapy in Children with Cancer" 3:35 PM: Coffee Break (30 min) 4:05 PM: Andrew Saykin, Psy.D., Indiana Alzheimer's Disease Center, Center for Neuroimaging, Indiana University School of Medicine “Advances in Imaging, Genetics and Biomarkers for Prodromal Alzheimer’s Disease” 4:45 PM: Joaquín Goñi, Ph.D., Department of Psychological & Brain Sciences, Indiana University “Network Measures Relating the Human Connectome to Resting-State Functional Connectivity” 5:30 - 7:00 PM: Poster Session and Cocktail Reception Wednesday, November 6, 2013 7:45 AM: Breakfast (30 min) 8:15 AM: Bernard Vrijens, Ph.D., MeadWestvaco Healthcare “Enrichment strategies for ambulatory clinical trials through measurement-guided management of patient adherence” 8:55 AM: John Urquhart, M.D., AARDEX Group “Minimum sampling rate of drug dosing histories to assure accurate, continuous, pharmacometric projections of internal drug exposure” 9:35 AM: Sean Mooney, Ph.D., Buck Institute for Research on Aging “Are We There Yet? Progress Toward Clinical Interpretation of the Human Genome” 10:15 AM: Coffee Break (20 min) 10:35 AM: Brian Topp, Ph.D., Eli Lilly and Company “Application of Physiologic-Based Models to the Development of Novel Therapies for Type 2 Diabetes” 11:15 AM: Timothy Waterhouse, Ph.D., Eli Lilly and Company “Evaluating Error Rates in Model-Based Predictions of Drug-Drug Interaction” 11:55 AM: Lunch (1 hr 10 min) 1:05 PM: Michael Heathman, Ph.D., Eli Lilly and Company “Concentration-Response Modeling of Adverse Event Data Using a Markov Chain Approach” 1:45 PM: Immanuel Freedman, Ph.D., GlaxoSmithKline Robert Bies, Ph.D., CTSI, Indiana University School of Medicine "Chaos Synchronization." 2:25 PM: Nieves Velez de Mendizabal, Ph.D., CTSI Disease and Therapeutic Modeling Program Division of Clinical Pharmacology, Indiana University School of Medicine "Understanding and Predicting Multiple Sclerosis: A computational Approach" Closing remarks: Robert Bies, Ph.D.