Pharmacometrics Network Benelux - Third meeting announcement

Dear Colleagues, It is a pleasure to invite you for the third meeting of Pharmacometrics Network Benelux. Please mark the following date and time in your agenda : When: Thursday, November 28th - 12:30 - 18:00 Where: Astellas , Advagraf & Prograf rooms, Mirai House, Sylviusweg 62, 2333 BE Leiden, The Netherlands Agenda theme: Modeling and simulation in pediatric drug development You can already register by sending an e-mail to Petra Bitter by Monday November 25th. E-mail: [email protected]<mailto:[email protected]>. There is no registration fee, but registration is required for participation. The format of the meeting will consist in 4 lectures and 2 "work-in-progress" sessions as successfully applied last spring. We would like to foster the interaction between participants and presenters with the work-in-progress presentations and the audience will have opportunity to provide input and direction. The meeting will include a light lunch, a coffee/tea break and some drinks afterward. Preliminary Program Lectures Predicting the efficacy of the Nanobody® ALX-0681 for the treatment of acquired thrombotic thrombocytopenic purpura (TTP) in pediatric patients - Massimiliano Germani, PhD, Ablynx Scaling PK to estimate first dose in children - Ashley Strougo, PhD, Astellas Model-based dosing rationale for darunavir when co-administered with low-dose ritonavir in pediatric HIV-1 infected patients - Anne Brochot, MSc, Janssen Work in Progress: Pharmacokinetic modeling and dose optimization of the polyclonal antibody Thymoglobulin in pediatric patients in stem cell transplantation setting - Rick Admiraal, MD; Department of Pediatric Immunology, University Medical Center Utrecht; Division of Pharmacology, LACDR, Leiden University; Department of Pediatrics, Leiden University Medical Center, Leiden Challenges in the prediction of dosages for new drugs in pediatric patients: the potential and limitations of application of semi-physiological models - Prof Catherijne AJ Knibbe, PharmD PhD; Division of Pharmacology, LACDR, Leiden University and St Antonius Hospital Nieuwegein There will be a security check when arriving at Astellas (ID required) and participant will receive a badge. Also, the parking capacity is limited so we encourage you to car pool or to use public transportation (Astellas premises are located 15 min walking from Leiden Central Station). We will provide you with route direction in the coming weeks. ***CALL FOR PRESENTERS*** : We are still looking for a volunteer to present some modeling work in pediatrics, please contact us ([email protected]<mailto:[email protected]>) if you want to participate. We hope to see you in Leiden on November 28! Anne Brochot Eugène Cox Rik de Greef Charlotte van Kesteren Thomas Kerbusch Catherijne Knibbe Ron Mathôt Stefaan Rossenu Jan-Stefan Van der Walt An Vermeulen On Pharmacometrics Network Benelux: the initiative aims to connect pharmacometricians in the Benelux (Belgium, Netherlands, Luxembourg). The intention is to create an informal platform for the pharmacometric community in this region of the world (in industry, academia, hospital pharmacies as well as regulatory bodies), with the goal to promote professional and scientific awareness and interactions. Stay tuned on our latest activity by joining our group on LinkedIn.