Pharmacometrics Tutorials

Dear Nmusers, We try not to bombard this distribution list with too many communications from CPT: Pharmacometrics & Systems Pharmacology (CPT:PSP), but thought it would be appropriate to draw your attention to various Tutorials on the foundations of Pharmacometrics that have been published recently: Basic Concepts in Population modeling and Model-Based Drug Development (D. Mould and R. Upton): Part 1: http://www.nature.com/psp/journal/v1/n9/full/psp20124a.html http://www.nature.com/psp/journal/v1/n9/full/psp20124a.html Part 2: http://www.nature.com/psp/journal/v2/n4/full/psp201314a.html http://www.nature.com/psp/journal/v2/n4/full/psp201314a.html A Time to Event Tutorial for Pharmacometricians (N. Holford): http://www.nature.com/psp/journal/v2/n5/full/psp201318a.html http://www.nature.com/psp/journal/v2/n5/full/psp201318a.html Modeling and Simulation Workbench for NONMEM: Tutorial on Pirana, PsN, and Xpose (R. Keizer, M. Karlsson and A. Hooker): http://www.nature.com/psp/journal/v2/n6/full/psp201324a.html http://www.nature.com/psp/journal/v2/n6/full/psp201324a.html Establishing Best Practices and Guidance in Population Modeling: an Experience with an Internal Population Pharmacokinetic Analysis Guidance (W. Byon et al.): http://www.nature.com/psp/journal/v2/n7/full/psp201326a.html http://www.nature.com/psp/journal/v2/n7/full/psp201326a.html http://www.nature.com/psp/journal/v2/n7/full/psp201337a.html http://www.nature.com/psp/journal/v2/n7/full/psp201337a.html As explained in a recent Editorial ( http://www.nature.com/psp/journal/v2/n7/full/psp201327a.html http://www.nature.com/psp/journal/v2/n7/full/psp201327a.html ), a CPT:PSP Tutorial is intended as an educational article providing practical tutorial on tools, methodologies, and approaches. Tutorials aim to increase the awareness and potential of Pharmacometrics and Systems Pharmacology outside the disciplines, introduce methodology to newcomers interested in model-based approaches, and provide further training and specialized guides to those already working in the field. The open-access format of CPT:PSP also provides an excellent platform by allowing efficient distribution to researchers worldwide. For most Tutorials, model code and example datasets will be available as supplementary material, allowing readers to practice the case studies 'hands-on'. More Tutorials will become available this year, the next one on Physiologically-Based Pharmacokinetics (PBPK). New articles are published weekly at www.nature.com/psp http://www.nature.com/psp Kind regards, Piet van der Graaf, Editor-in Chief Lena Friberg, Deputy Editor-in-Chief CPT: Pharmacometrics & Systems Pharmacology (CPT:PSP) [email protected] <mailto:[email protected]>