refernce period bayesian estimates "carried-forward"
Dear Users,
I works on a model describes IVIVC using the approach described by Gaynor et al
2011.
The input data come from a cross-over study with a reference period (imediate
release).
I would like to use the KA bayesian posthoc estimates of this refernece period
for all other periods unchanged.
My question is, how can I separate this period from the rest ones to ensure
that nonmem does not fit this parameter other periods, but the reference?
Thanks,
István
István Németh PhD
Developmental Drug Metabolism & Pharmacokinetics
Pharmacological and Drug Safety Research
Gedeon Richter Plc
Tel: 00 36 1 505 7082
Fax: 00 36 1 889 8526