Installation of both NONMEM 7.2 and Phoenix WinNonLin 6.x

________________________________________ From: Kevin Dykstra [mailto:[email protected]] Sent: Thursday, November 15, 2012 5:14 PM To: Simon Davis; Bauer, Robert; [email protected] Cc: [email protected] Subject: RE: installation of both NONMEM 7.2 and Phoenix WinNonLin 6.2 All, To be clear, the solution Simon describes is exactly the one that I found to work in my case. Using the nonmem/fortran/MPICH installation package did not, by itself, take care of the problem. I needed to manually edit the path as described below. Best, Kevin From: Simon Davis [mailto:[email protected]] Sent: Thursday, November 15, 2012 4:56 PM To: Kevin Dykstra; Bauer, Robert; [email protected] Cc: [email protected] Subject: RE: installation of both NONMEM 7.2 and Phoenix WinNonLin 6.2 Roger, Kevin, For others who have reported this issue we have found that editing the path in the system environment so that gfortran comes ahead of the Pharsight software solves this problem. In other words, edit your path so that c:\Program Files\gfortran\libexec\... comes first in the path, before C:\PHSTMinGW. Are you saying you've done that and still have an issue? If so please contact [email protected] and we will try to assist on our side as well to understand better where this conflict comes from on a small number of configurations. Best regards, Simon. ___________________________________ [email protected] Senior Scientific Consultant Pharsight- A CertaraT Company March 2012 Phoenix 6.3, including the new QRPEM algorithm for NLME released, get tips and discuss Pharsight products with other users; www.pharsight.com/extranet ___________________________________ http://www.pharsight.com/training/training_upcoming.php From: [email protected] [mailto:[email protected]] On Behalf Of [email protected] Sent: Thursday, November 15, 2012 9:05 AM To: [email protected] Subject: [NMusers] installation of both NONMEM 7.2 and Phoenix WinNonLin 6.2 Dear Nonmem users, Recently we have tried to install Nonmem 7.2 on a Dell Precision T5500, 12 core Xeon running windows 7 Pro SP1 in 64 bit mode. We used the workaround posted on the archive by William Bachman on Wed, 9 May 2012. Nonmem did however not compile using the gfortran 4.6.0. compiler, nor using gfortran 4.6.3. Variables were set as follows: LIBRARY_PATH C:\Program Files (x86)\gfortran\lib PATH C:\Program Files (x86)\gfortran\libexec\gcc\i586-pc-mingw32\4.6.0; C:\Program Files (x86)\gfortran\bin; TEMP %USERPROFILE%\AppData\Local\Temp TMP %USERPROFILE%\AppData\Local\Temp On the computer Phoenix WinNonLin 6.2 was pre-installed. This included the MPICH2 software for multiple CPU and CPU core processing. Phoenix does add strings to the system environment variables. Unfortunately, I don't have these available (or a screenshot) to share anymore. After de-installation of Phoenix 6.2 and MPICH2, the compilation of Nonmem went smoothly. Apparently, the presence of Phoenix software (including references in the environment variables for Phoenix) in our case, prevented adequate installation of Nonmem. Has anybody experienced similar problems? If so, can you advice me on a workaround enabling co-installation of both NonMem and Phoenix WinNonLin on a single machine? Many thanks for the input. Roger R.J.M. Brüggemann, PharmD, PhD Hospital Pharmacist, Clinical Pharmacologist (it) Radboud University Nijmegen Medical Centre Department of Clinical Pharmacy, 864 and Nijmegen Institute for Infection, Inflammation and Immunity (N4i) Geert Grooteplein 10 6525 GA Nijmegen The Netherlands T: +31.24.3616405 / Pager: *813148 F: +31.24.3668755 @: R.Bruggemann(at)akf.umcn.nl Het UMC St Radboud staat geregistreerd bij de Kamer van Koophandel in het handelsregister onder nummer 41055629. The Radboud University Nijmegen Medical Centre is listed in the Commercial Register of the Chamber of Commerce under file number 41055629.