Re: VPC question
Hi Norman,
you can use below for 80% PI
xpose.VPC("vpc_results.csv",vpctab="vpctab",PI.limits = c(0.1,
0.9),ylb="Concentration ng/mL")
kun wang
Quoted reply history
From: Norman Z
Sent: Tuesday, October 09, 2012 7:30 AM
To: [email protected]
Subject: [NMusers] VPC question
Dear NMusers,
I am using PsN to conduct VPC. A “vpc_results.csv” was generated by PsN, where
the percentiles of real and simulated data were reported. Generally, these
percentiles plus the observed data were used for the VPC plot. My question is
how to calculate number of observation outside the 90% prediction interval
(PI). I am thinking about two way to do this.
First, I may use the NPC results provided by the “vpc_results.csv” file, e.g.
NPC results
bin 3: 15 observations
points below PI (count) points below PI (%) ...
0% PI 7
46.66667 ...
40% PI 5
33.33333 ...
80% PI 1
6.66667 ...
90% PI 0 0
...
95% PI 0 0
...
Should the numbers in this table be used to obtain the observation outside the
90% PI? If so, how can they be used?
If not, shall I calculate the observation outside the 90% PIs of each bin using
R?
Second, I can calculate the 90% PIs for each time point (e.g. 1.1h, 1.3h, etc)
from the raw simulated data and compare the 90% PIs with the observation at one
particular time point. Would the second strategy be more accurate than
calculate the observation outside the 90% PIs of each binned time interval
(e.g. 1-2 h, 2-3 h)? If this is the case, where can I find the raw simulated
data? (I suspect the “DV_matrix.csv” and “vpc_simulation.1.npctab.dta” in “m1”
folder are the raw simulated data, but want to refer to relevant document to
understand how these files are organized.)
Thanks for your help.
Norman