omega matrix - friendly suggestion
Hello NONMEM Community,
Sometimes it takes more time to choose the best omega matrix than to develop a
PD model. Selecting the omega matric is a tedious, time consuming and less
creative part of the model development. I hope you feel my pain. Will it be
helpful to rewrite the NONMEM software so that any element of the omega matrix
can be fixed to any value? It may look like this:
$OMEGA BLOCK (4) 3.60E-02 FIX
0.01 3.23E-02
0.03 0 FIX 1.66E-02
0.01 0 FIX 0.03 FIX 1.66E-02
This change can make many NONMEM users happy.
Thanks!
Pavel