Re: VPC results using PsN and Xpose
Or, maybe it's bin problem.
Kun Wang
'[email protected]'<[email protected]>;
-----Original Message----- From: Leonid Gibiansky Sent: Thursday, May 10, 2012 10:58 AM To: Toufigh Gordi Cc: ' [email protected] ' Subject: Re: [NMusers] VPC results using PsN and Xpose
Toufigh
It would help to see the plot. One possibility is that the plot is in the log scale, and you have additive error component that plays larger role at low concentrations.
Leonid
--------------------------------------
Leonid Gibiansky, Ph.D.
President, QuantPharm LLC
web: www.quantpharm.com
e-mail: LGibiansky at quantpharm.com
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Quoted reply history
On 5/10/2012 12:49 PM, Toufigh Gordi wrote:
> Dear all,
>
> We have performed a VPC using PsN and the results were plotted using
> Xpose 4. An interesting feature of the graph is that the outer limits of
> the interval do not follow the typical curve smoothly but change with
> the observed data. As an example, toward the end of the time interval,
> where we have a larger variability in the observations, the lines widen
> and capture most of the data. I have difficulties understanding why the
> prediction lines behave this way. Any comments?
>
> Toufigh