Fw: Open position at Merck Serono for a skilled M&S scientist

Merck Serono is the division for innovative small molecules and biopharmaceuticals of Merck KGaA. We are searching for a senior scientist, Modeling & Simulation (M&S), to strengthen our group dedicated to projects in the Neurodegenerative Diseases and Rheumatology areas, and potentially support projects in Oncology. The position is open in Germany (Darmstadt) and Switzerland (Geneva). Job description: As a successful candidate, you will influence Preclinical to Phase I transitions and drug development strategies, as well as support the demonstration of Proof of Confidence in the clinic, in collaboration with non-clinical modelers, clinical pharmacologists, clinicians and biostatisticians. Your main tasks and responsibilities are: · Globally support the M&S department within Exploratory Medicine, as well as Clinical and Projects Teams · Provide M&S input into Translational Research and Clinical Development Plans · Plan, perform, interpret, present, track and record pharmacometric activities within allocated projects and studies · Develop internal expertise in advanced population PKPD modeling, with emphasis on physiological and mechanistic approaches and disease progression models · Explore, evaluate and implement appropriate pharmacometric tools and methodology, including Trial Simulation to support optimal design of clinical trials · Participate to the improvement of the M&S processes and technological platform · Keep up-to-date with scientific development in M&S, and regulatory guidance and trends · Facilitate communication with authorities and all other stakeholders. Qualifications: You would have acquired a PhD and at least 3 years experience in population PKPD and drug disease models (of which at least 1 year in the biopharmaceutical industry, with M&S input into drug development). Good command of NONMEM software is an absolute prerequisite; experience with complementary method(s) and software would be an asset, together with knowledge of relevant programming languages (R, in particular). Interest in, and knowledge of both mathematical and (patho-)physiological aspects of M&S in drug development is taken for granted. Good communication skills in oral and written English are a must. You should have high personal integrity, strong problem solving skills and ability to analyze complex problems, be a team-player, enthusiastic and self-motivated, and at ease in working in a dynamic matrix organization. The ability to discuss with external experts and CROs would round off you profile. Merck Serono is committed to foster M&S in drug development, and offers a chance to work amongst the most talented colleagues from around the world, to be part of inspirational teams and to make a personal difference. In return for your contribution, you can look forward to working in an unusually stimulating and rewarding environment. To find out more and to apply, please visit http://www.merckserono.com/en/careers/index.html (Advanced Search: job number 1201045) Alain Munafo Head of Modeling & Simulation, Global Exploratory Medicine, Merck Serono S.A., Geneva This message and any attachment are confidential and may be privileged or otherwise protected from disclosure. If you are not the intended recipient, you must not copy this message or attachment or disclose the contents to any other person. If you have received this transmission in error, please notify the sender immediately and delete the message and any attachment from your system. Merck KGaA, Darmstadt, Germany and any of its subsidiaries do not accept liability for any omissions or errors in this message which may arise as a result of E-Mail-transmission or for damages resulting from any unauthorized changes of the content of this message and any attachment thereto. Merck KGaA, Darmstadt, Germany and any of its subsidiaries do not guarantee that this message is free of viruses and does not accept liability for any damages caused by any virus transmitted therewith. Click http://www.merckgroup.com/disclaimer to access the German, French, Spanish and Portuguese versions of this disclaimer.