Re: Mixed Models

From: Indrajeet Singh Date: March 21, 2012 technical Source: mail-archive.com
Shankar: I hope you are not, but you can not change true value variables in conditional statements eg. IF (...) THEN CL= TVCL+eta(1) ELSE CL=TVCL+eta(2) ENDIF There are alternate ways of doing that by creating new identifier for your WT ranges. I hope this helps.
Quoted reply history
On Wed, Mar 21, 2012 at 10:39 AM, Shankar Lanke <[email protected]>wrote: > Dear All, > > I am running a pop pk IV infusion data, the observed values are collected > form obese patients and normal patients. > I used WINONLIN to estimate the initial parameters. Patients who weigh > more than 350 lbs are following 2CM and less than 350 are following 1CM. > I confirmed the models based on AIC, CV% (of parameters), graphical > representation. Vd increases with weight (1CM). > > So I used IF(WT<=350)THEN statements from the beginning ($MODEL, $ PK, $ > DES, $THETA). I have the following error. > AN ERROR WAS FOUND IN THE CONTROL STATEMENTS. > > AN ERROR WAS FOUND ON LINE 10 AT THE APPROXIMATE POSITION NOTED: > IF(WT<=350)THEN > X > THE CHARACTERS IN ERROR ARE: IF > > Thank you very much in advance for your suggestions. > > > Regards, > Shankar Lanke Ph.D. > > -- Indrajeet Singh,PhD Sr. Clinical Pharmacokineticist Abbott Labs, North Chicago, IL
Mar 21, 2012 Shankar Lanke Mixed Models
Mar 21, 2012 Indrajeet Singh Re: Mixed Models
Mar 21, 2012 Nick Holford Re: Mixed Models
Mar 24, 2012 Shankar Lanke Re: Mixed Models