Pfizer China opportunities

Pfizer (China) Research & Development Center, Shanghai Clinical Pharmacology/Pharmacometrics: Pharmacometrician I & II (Pharmacometrician I - D2A / Pharmacometrician II - D2B) In this key role as a member of our industry leading Global Pharmacometrics group you will be responsible for conducting and reporting population PK/PD analyses, following Pfizer best practices, to support projects of our various Research and Business Unit organizations. Of key importance will be the formation and maintenance of effective collaborations with other pharmacometricians and clinical pharmacology leads of the global Pfizer. Key Responsibilities: General Project Support Responsibilities * To form effective collaborations with clinical pharmacology leads as well as the project pharmacometricians, in particular disease area points of contact, to deliver high-quality population PK/PD analyses to support projects of our various Research and Business Unit organizations. * To plan effectively so as to achieve appropriate timescale for successful completion of each population PK/PD analysis and report, working in collaboration with appropriate colleagues. * Based on the analysis outline, draft the population modeling analysis plan for review and feedback by the project team. * Consistent with the analysis plan, submit and review dataset requests to ensure that datasets generated are appropriate for the analysis plan and are of a sufficient standard to satisfy GCP and Regulatory Authority submissions. * To conduct and report population PK/PD analyses, generate parameters and appropriate diagnostic plots, following Pfizer best practices. * To conduct analysis review sessions with the project team, as necessary, to confirm emerging and draft results. * To draft the population modeling analysis report, including all results and appendices, for review and comments by the project team. * To manage team reviews and updates to finalize the analysis report appropriately. * To participate in peer review and quality control activities as part of the analysis reporting process * To submit the finalized report to the appropriate document repository for publishing Specific Pharmacometric Line Responsibilities * To share learning's and participate in peer review meetings with other Pharmacometricians. * Contribute to the Pharmacometric group remit in implementing standards in order to achieve consistency in the population PK/PD analyses across RU/BUs. * Promote, educate and mentor others in application of quantitative techniques and participate in and share experiences through appropriate local and global discussions. * Work to increase the visibility and effectiveness of Pharmacometrics, promoting the use of quantitative principles through active contributions (presentations or publications) at internal and external meetings. * To keep abreast of developments in the field of Pharmacometrics and ensure line colleagues are kept up-to-date with the relevant scientific developments. Candidate Specifications: Ideally you will be a graduate with an applied and/or methodological PhD or MSc in a relevant field of computer modelling, Pharm.D or M.D,. with a minimum three years' experience (including graduate training) in pharmacokinetics/clinical pharmacology/statistics, medicine or a related discipline and an excellent understanding of the drug development process. However, candidates from an alternative background e.g. mathematics, engineering, system biology will be considered if they can demonstrate relevant experience and expertise. Data modelling and good communication skills in English (written and oral presentations) are essential for this role. The successful candidate will have published or presented in the field of exposure response modelling and will be familiar with NONMEM and/or other data analytical tools S-Plus, WinBugs, SAS etc. On top of above requirements, the successful candidate for Pharmacometrician II will have about two years or more industry experience in the popPK/PD modeling, and have real world experiences in the popPK/PD analysis and reporting in a regulatory compliant environment. Competency Requirements: * A self-motivated, clear thinking person who is well organized and can operate independently under broad direction. * A person who can achieve results through effective collaborations with the teams, and functional groups upon which they depend for the delivery of population analyses. * The ability to relate to, and communicate with development and operational staff across a range of disciplines throughout the company. * Possession of effective verbal and written English communication skills in relating to colleagues both inside and outside the organization. * The ability to advise and guide colleagues in a supportive and encouraging fashion ensuring that deadlines are agreed, set and achieved. * A diplomatic person who can develop and maintain the existing good relationships, gain the confidence of other professionals, present and argue a case, and strongly influence contentious discussions in a constructive manner. * Proactive in seeking new information/developments in the technical arena. * Keen and able to work in a team environment, with a collaborative approach to interactions at work. * Comfortable in mentoring and motivating cross functional teams in complex quantitative methodologies and techniques. * Able to adapt quickly to working within a regulated industry, and to demonstrate flexibility when constraints/conflicts become evident. Please send your CV to Lucy Chen of HR Talent Acquisition ([email protected] <mailto:[email protected]> ).