Disease progression modeling for Cancer

Dear All, We are working on developing a quantitative model for cancer progression. Major studies in this area, including non-small cell lung cancer (NSCLC) model from FDA, follows a similar approach to model a) change in tumor size over time and b) survival model: which includes tumor stage and tumor size as predictors of overall survival. We are still looking to get hold of a good data set that has time dependent values of variables. I have contacted the aurhors of various published studies, but its not easy. Any suggestions about sources from where we can get this type of data set? In addition, I am trying to collect data from literature that I can use in my research. We do not see detailed information in articles about the time dependent change in the variables like tumor size. Most of the literature show Kaplan meier curves with the mean/median survival times with different treatments, tumor size and stage at the time of diagnosis. What would be the best way to start this modeling exercise given the limited amount of data that I am able to collect? Thanks, Gaurav -- Gaurav Bajaj Postdoctoral Fellow, Pharmacometrics Laboratory for Applied PK/PD Clinical Pharmacology & Therapeutics The Children's Hospital of Philadelphia