Re: Two sequential absorption processes

From: Paul Matthias Diderichsen Date: April 12, 2011 technical Source: mail-archive.com
Hi Liu, One reason why you don't get the expected result with your current code is that you probably confuse TIME (which is the time of the current record) and T (which is the "running" time in the $DES block).
Quoted reply history
On 4/6/2011 3:33 PM, Liu Dongyang wrote: [...] > $DES > IF (AMT.GT.0) THEN > TDOS=TIME ;dosing time ... this is correct [...] > IF (TIME .LE. TDOS) THEN ; for PD baseline [...] > IF (TIME .LE. TL .AND.TIME .GT. TDOS ) THEN ... here, you should probably use T instead of TIME. However, I'd vote for "putting the model into the data" as Luann suggested by using two dose records; one for the zero-order and one for the first order absorption. Kind regards, -- Paul Matthias Diderichsen, PhD Quantitative Solutions B.V. +31 624 330 706
Apr 06, 2011 Liu Dongyang Two sequential absorption processes
Apr 07, 2011 Mahesh Samtani RE: Two sequential absorption processes
Apr 07, 2011 Murad Melhem Re: Two sequential absorption processes
Apr 11, 2011 Luann Phillips Re: Two sequential absorption processes
Apr 12, 2011 Paul Matthias Diderichsen Re: Two sequential absorption processes