New Metrum Institute Course on Bayesian Model-Based Meta Analysis, plus WinBUGS Intro

Metrum Institute* is pleased to announce a new hands-on, intensive 3- day course (MI260+) scheduled for September 2, 3, & 4, 2009 in Cambridge, MA. This offering will combine an introduction to WinBUGS for pharmacokinetic/pharmacodynamic applications, with a detailed overview of Bayesian model-based meta analysis. Getting Started with Bayesian PK-PD Modeling (Day 1): This introductory course covers the basics of Bayesian modeling theory and the use of WinBUGS for PK-PD applications, including: running WinBUGS from R, nonlinear mixed effects models for PK and PD endpoints, population PK, BQL data, and the new BUGSModelLibrary for PKPD applications. Model-Based Meta-Analysis to Support Decision Making in Clinical Drug Development (Days 2 and 3): MI260 provides an introduction to model- based meta-analysis of summary data or combinations of summary and individual data, and the rationale for applying Bayesian modeling methods to these problems. Hands-on modeling topics, using WinBUGS include: dose-response models for landmark and longitudinal summary and individual data, as well as population simulations from meta- analysis models. Location: Le Meridien Hotel, 20 Sidney Street, Cambridge, MA Hardware/Software: Participants will be expected to bring their own Windows-based laptop, and software installation instructions will be provided separately. All software tools are freely available or open- source. Registration: To register, or for more details see http://metruminstitute.org/ and select "All Courses" from the Training Courses menu on the left- hand side of the page. *Metrum Institute is a 501(c)(3) non-profit organization. As always, Metrum Institute training course revenues support continued development of open-source tools for the pharmacometrics community, such as the BUGSModelLibrary. Thanks to all who have supported MI in the past. Marc R. Gastonguay, Ph.D. Scientific Director, Metrum Institute [www.metruminstitute.org]