NONMEM 7 Distribution

Dear NMusers : NONMEM 7 must be distributed as encrypted source code. An installation program will be included. The SIZES file and several other resource files will be left unencrypted so that the user can make desired changes prior to compilation as was possible with previous versions. Because compiling and linking will be performed in the users environment it should be possible to avoid the problems encountered during beta testing. This is a much better solution than distributing only binary code for a very limited number of computing environments. This change in our method of distribution will require that a revised licensing agreement be executed. This agreement will be sent to the contact person for each license in the next few weeks and must be signed and returned before NONMEM 7 will be sent to the licensee. ICON Development Solutions has made a multimillion dollar investment in this version of the software and has a commitment to its continued development. We understand that some members of the user community are dissatisfied with this decision; but, the general release of source code would conflict with our legal and financial commitments to this software. Stuart Beal placed NONMEM in a commercial environment with the hope that its development would be sustained. This decision is in keeping with Stuart's intent. Source code could be shared under a special licensing and confidentiality agreement for a collaborative project that would contribute to the continued development of NONMEM. Such a project will usually require a formal proposal and a list of deliverables. NONMEM VI 2.0 will no longer be distributed after the release of NONMEM 7 but users may continue to use NONMEM provided they have a currently valid NONMEM license. All previous releases of NONMEM are the property of the Regents of the University of California, but ICON Development Solutions continues to have exclusive rights to license their use. Gracelyn A McDermott, MBA, PMP Vice President, Business Development ICON Development Solutions Michael Fedock, MBA Vice President, Finance ICON Development Solutions Buzz Krohn, J.D. Director, Legal Affairs ICON Development Solutions