Re: RE: NONMEM 7 Update
The fact that NONMEM7 will not be open source code is very unfortunate,
it has not been often, but there have been occasions when by going over the
source code I was able to understand aspects of NONMEM programming that were
still unclear to me,
being able to get a look at the actual algorithms in software had been a major
advantage for NONMEM!!!!
Alice I Nichols, PhD
Sr Director
Early Development and Clinical Pharmacology
Wyeth Research
500 Arcola Rd
Collegeville, PA 19426
tel: 484-865-8741/ fax: 484-865-9075
[email protected]
>>> "Serge Guzy" <[email protected]> 7/3/2009 3:56 AM >>>
I do have only one simple question. How many people took advantage from the
fact Nonmem was distributed as open source? If we are talking about a very
small percentage, is this discussion worthwhile? How many people except bob
bauer and may be somebody else I am not aware of are able to follow and
understand the cuirrent nonmem code?
Serge
Quoted reply history
From: [email protected]
To: Ludden, Thomas ; [email protected]
Sent: Thu Jul 02 23:46:09 2009
Subject: [NMusers] RE: NONMEM 7 Update
Thomas Didn't ICON consider that indeed, this decision might stimulate the
divergence of an open-source clade of NONMEM, somewhat like R stemmed out of
S-plus? If a small academic group starts to work in that direction, it would
certainly be quickly joined by many* Thierry BuclinUniv. Hospital, Lausanne De
: [email protected] [mailto:[email protected]] De la part
de Ludden, Thomas
Envoyé : jeudi, 2. juillet 2009 15:15
À : Eleveld, DJ; [email protected]
Cc : Krohn, Anthony
Objet : RE: [NMusers] NONMEM 7 Update
Dear All:Icon Development Solutions has invested in the further development of
NONMEM. By mutual agreement with the University of California at San
Francisco, NONMEM 7 is intellectual property belonging to IDS. However, IDS
will continue to pay royalties to UCSF. The business plan under which NONMEM
7 was developed calls for the protection of the I.P. involved. In addition,
NONMEM 7 contains several updated routines developed and owned by IMSL (Visual
Numerics Inc.). Our agreement with IMSL stipulates that we will not distribute
their source code. The installer will compile the software but will not allow
the unencrypted source code to remain on the users computer. The licensing
agreement will also stipulate that any attempt to access the source code will
be a violation of the agreement. Some source code will be left unencrypted for
various reasons, one being the need for users to change certain values in SIZES
and perhaps other resource routines.Tom
Thomas M. Ludden Ph.D.
Vice-President, Pharmacometrics R&D
ICON Development Solutions Tel: + 1 410 696 3040
Mob: + 1 410 258 2411
Fax: + 1 410 480 0776
Email: [email protected]: www.icondevsolutions.com
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