Bootstrap analysis

Group: I have bootstrap analysis (my first) parameter estimates and model parameters. The PDxPOP/NONMEM manual I have does not provide any guidance as to how I can statistically compare these two (or do I need to?). I also have histograms for the thetas in bootstrap analysis. I can make some visual judgements but is there a way to statistically compare the two results (bootstrap v model) built in to the NONMEM that I can use to quickly get some statistical comparison results? How else can I use the bootstrap results to confirm the fact that the model I have is the best fit for the data? Thanks in advance. Varsha Mehta, MS(CRDSA), Pharm.D., FCCP Clinical Associate Professor Pharmacy, Pediatrics and Communicable Diseases Clinical Pharmacist Neonatal Critical Care University of Michigan (O) 734-936-8985 (F) 734-936-6946 [email protected] ********************************************************** Electronic Mail is not secure, may not be read every day, and should not be used for urgent or sensitive issues