Re: Code for EHC

Dear Ayyappa: I think you will find the following nmusers net post useful for your model. Alison had kindly provided some code for a EHC model. Best regards, Sam Liao Pharmax Research =================================================================== *Enterohepatic Recirculation Model < http://www.cognigencorp.com/nonmem/nm/98oct061998.html >* *|... |*this compartment to the change-point. Based on these ideas, here's how I would modify Rik's code. The change also provides for the termination of *EHC http://www.cognigencorp.com/nonmem/nm/98oct061998.html#pgfId=424161*. If you want to let *EHC* continue indefinitely, delete compartment 6 and its dose, and the code involving ALAG6. 1) Add 2 more compartments to $MODEL:*| ...|* / http://www.cognigencorp.com/nonmem/nm/98oct061998.html/ 05/06/03, 19876 bytes > Dear All, > > I am trying to model PK data of a drug and many subjects show double peaks but even in fasting state. Can we expect EHC in fasting state? Can anybody provide some coding help in modeling intermittent episodes of EHC rather than continuous mode? > > Thank you. > > Regards, > Ayyappa Chaturvedula