Interesting job position within Discovery PKPD

From: Johan Gabrielsson Date: August 20, 2008 job Source: mail-archive.com
Advanced PKPD scientist in Drug Discovery (Astrazeneca R&D, Mölndal, Sweden) We are looking for an experienced (> 3 years post PhD experience) Pharmacokineticist/PKPD scientist to our PKPD section with a key responsibility to develop and apply PKPD strategies, study designs and analyses within the Drug discovery phase within one of our most prioritised Disease area segments, Diabetes and Obesity. The arena As one of the world´s leading Pharmaceutical companies, our business is focused on turning good ideas into innovative, effective medicines that make a real difference in important areas of healthcare. AstraZeneca is one of the world's leading pharmaceutical companies, with a broad range of medicines designed to fight disease in important areas of healthcare. Backed by strong science and wide-ranging commercial skills, we are committed to sustainable development of our business and the delivery of a flow of new medicines that make a difference in the lives of patients and create value for our shareholders and wider society. We are active in over 100 countries with growing presence in important emerging markets; corporate office in London UK; major R&D sites in Sweden, the UK and the US. The position is placed within the PKPD section of the Dx DMPK Department within the Research area CVGI (Cardiovascular and Gastrintestinal research) in Mölndal, Astrazeneca, R&D Sweden. The position offers a great opportunity to apply your pharmacokinetic and PKPD skills by implementing our PKPD based Drug Discovery strategy and applying state of the art PKPD study design and analyses within one of our most prioritised Disease areas. You will work in an advanced Drug Discovery setting together with other highly competent PKPD and Pharmacology scientists. The role One of your main responsibilities will be to represent the Discovery DMPK Department in a cross functional Disease area Team and be responsible for developing PKPD strategies for all new projects emerging within a segment of the Disease area. By applying state of the art PKPD principles in study design and analyses, you will actively contribute to · Target validation studies for emerging targets · Develop PKPD strategies and establish a PKPD understanding for new targets and chemical classes in relation to critical Milestone decisions. · Generate preclinical PKPD data for potential Candidate drugs including translational aspects and assure a good transfer of knowledge into the Development organisation In addition you will be critical in the development and spreading of the PKPD competence and the general PKPD strategy within the Research Area. The role does not include responsibility for staff and you report directly to the Head of the PKPD section. Minimum experience/requirements · A PhD (or equivalent experience) in pharmacokinetics/PKPD with >3 years of industry or academic post PhD experience · Excellent understanding of drug disposition and pharmacological principles · Demonstrated hands-on Modeling experience from e.g. WinNonlin · Proven leadership capabilities · Excellent English - written and verbal communications skills · A collaborative, open minded and team oriented spirit Preferred experience/requirements · Experience from the application of PKPD in Drug Discovery is a clear merit · Experience from Population modeling (e.g NONMEM) is of additional value More information For more information, please contact Dr Ulf Bredberg, Head of PKPD Section Phone: +46 (0) 705 86 13 98. To apply: You apply via our homepage at Astrazeneca.com. Click on careers then Job opportunities and then locate the position. Then follow the instructions. Closing date: August 31