examples of PKPD modeling in pre-clinical drug development

From: Fatemeh Akhlaghi Date: May 02, 2008 technical Source: mail-archive.com
Dear nmusers I am looking for a few example of the use of PK/PD modelling in the pre-clinical development that has positively improved the development process i.e. reducing the TIME or COST of development. Any suggestions or leads will be greatly appreciated. Many thanks Fatemeh