NEW Spring/Summer Metrum Institute Training: Basic Population PKPD & Bayesian PKPD Modeling for Continuous and Odd-Type Data

[apologies for duplicate postings] Metrum Institute spring/summer 2008 training course offerings include three intensive, hands-on, courses. Two of these courses are repeat- performances of popular topics, including essential skills in population PKPD and Bayesian PKPD modeling methods. The third is a new offering focused on Bayesian methods for analyzing odd-type PD data: MI210: Essentials of Population PKPD Modeling & Simulation, May 19-21, Philadelphia, PA MI250: Introduction to Bayesian PK-PD Modeling & Simulation, July 16-18, Bar Harbor, ME * MI255: Exposure-Response Modeling of Categorical, Count and Time-to- Event Data Using Bayesian and Maximum Likelihood Methods, July 19-21, Bar Harbor, ME * (*Discounted group rate blocks for hotel rooms at the Bar Harbor courses will be determined by April 1st. Later registrants will not be guaranteed group rates.) Attendance will be limited to 20 participants for each course. Discounted course fees are available for academics/non-profits. Please see brief course descriptions below and additional details at: http://metruminstitute.org/training/index.html . Thank you, Marc Marc R. Gastonguay, Ph.D. Scientific Director, Metrum Institute [www.metruminstitute.org] Direct: 860-670-0744 Main: 860-735-7043 Email: [EMAIL PROTECTED] MI210: Essentials of Population PKPD Modeling & Simulation ------------------------------------------------------------------------------------ MI210 provides an extensive overview of essential topics in population pharmacokinetics and pharmacodynamics, including: nonlinear-mixed effects modeling theory and implementation, data formatting requirements, population model development, model evaluation techniques, continuous PK-PD models, Monte Carlo simulation, and best practices. Instruction combines didactic lectures with hands-on exercises using R and the NONMEM® software. Prerequisites: Basic understanding of pharmacokinetic and pharmacodynamic principles, compartmental pharmacokinetic models, introductory statistics, familiarity with the R or S language. Applicable MI Courses include: MI120, MI101, MI201, or contact instructor. May 19-21, 2008 9:00AM-5:00PM Eastern time Children's Hospital of Philadelphia Philadelphia, PA register online now at http://metruminstitute.org/training/index.html MI250: Introduction to Bayesian PK-PD Modeling & Simulation ------------------------------------------------------------------------------------ MI250 is an intensive, 3-day onsite course that provides an introduction to Bayesian modeling and the practical use of WinBUGS and R for PK-PD applications. Prerequisites: Experience with PK-PD modeling and some familiarity with nonlinear regression, mixed effects modeling and R (or S-Plus) is requred. Applicable MI courses include: MI 210 and MI212. July 16-18, 2008 (Wed-Fri) 8:30AM-4:30PM Eastern time The Harborside Bar Harbor, ME register online now at http://metruminstitute.org/training/index.html MI255: Exposure-Response Modeling of Categorical, Count and Time-to- Event Data Using Bayesian and Maximum Likelihood Methods ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- MI255 provides and introduction to modeling of categorical, count, and time-to-event data, and the practical use of NONMEM® and WinBUGS for such applications. Prerequisites: Experience with PK-PD modeling and some familiarity with nonlinear regression, mixed effects modeling and R (or S-Plus) is required. Prior experience with Bayesian modeling using WinBUGS is desirable but not required. The course includes a short introduction to Bayesian principles and WinBUGS. Applicable MI courses include: MI210, MI212 and MI250, or contact instructor. July 21-23, 2008 (Mon-Wed) 8:30AM-4:30PM Eastern time The Harborside Bar Harbor, ME register online now at http://metruminstitute.org/training/index.html