Is the use of II, SS, and ADDL allowed simultaneously
Dear NMusers,
Is the use of II, SS, and ADDL allowed simultaneously in NONMEM?
I wish to assess PK profiles at SS with and without compliance. Here is the
potential scenario I am interested in:
i) Patients come in at SS and take their 1st two doses correctly
ii) Patients then remain compliant OR miss a dose OR ingest a double dose
iii) Patients then resume taking their doses correctly
For (i) I will need II, SS and ADDL
For (ii) I don't need any II or SS or ADDL
For (iii) I will need II and ADDL
Kindly advice...Mahesh
PS. I am aware that I can hard code (formatting via S-plus etc) each dose after
the first SS dose as a separate dosing record but I wish to know if there is an
easier method available