REML implementation in NONMEM
Dear all,
In the Yano, Beal & Sheiner paper that appeared in JPKPD vol 28(4) 2001:
pg 389-412, the use of restricted maximum likelihood (REML) is
discussed. In that paper the reader is referred to an old nonmem
repository for its (apparently nontrivial) implementation in NONMEM.
That link unfortunately is not alive anymore. So my question is: Could
someone please provide me with a REML implementation for NONMEM or the
aforementioned material?
Best regards,
Jeroen
J. Elassaiss-Schaap
Scientist PK/PD
Organon NV
PO Box 20, 5340 BH Oss, Netherlands
Phone: + 31 412 66 9320
Fax: + 31 412 66 2506
e-mail: [EMAIL PROTECTED]
PS: pubmed link to Yano article is
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uid
s=11677933&dopt=Citation
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