Absorption delay NOT completed before the next dose is given
Dear NM users,
NM help files says the following about ALAG
"When additional doses are specified on a dose event record, the absorption
lag time applies to the dose and to all the additional doses. In this case
the lag time should not exceed the (length of the) interdose interval"
My questions are
a) Why doesn't ADDL work for the above specific case?
b) I am running linear models with ADVAN2 and ADVAN5 and absorption delay
is NOT completed before the next dose is given. Due to the problem stated
above I am not using ADDL. Instead I have a dosing record at every time a
dose enters the depot compartment. Will this circumvent the problem stated
above? In other words does ALAG always have to be smaller than II and why?
Please advice…MNS