Re: create simulation file for 5000 patients ?

On Feb 28, 2007, at 6:42 AM, Mark Sale - Next Level Solutions wrote: > Dennis, > > I'll show you how to do it in Excel someday. But the answer is to use > > the SUBPROBLEMS option in the SIMULATION record > > SUBPROBLEMS=n > Requests that the entire NONMEM problem is to be repeated n times > in succession (including all NONMEM steps: simulation, estima- > tion, covariance, table, scatterplot). Each subproblem includes > the Simulation Step, but the random sources are simply continued > from subproblem to subproblem. If n=0 or n=1, there is only one > subproblem; this is the default. May also be coded SUBPROBS, > NSUBPROBLEMS, NSUBPROBS. > > Mark Sale MD > Next Level Solutions, LLC > www.NextLevelSolns.com > > > > -------- Original Message -------- > > > Subject: Re: [NMusers] create simulation file for 5000 patients ? > > > From: "navin goyal" <[EMAIL PROTECTED]> > > > Date: Tue, February 27, 2007 10:28 pm > > > To: "Dennis Fisher" <[EMAIL PROTECTED]>, [email protected] > > > > > > thanks for the reply. > > > > > > Could excel help me if I had less patients say around 100-200. > > > I mean.. could i generate an excel file then ?? > > > How could I do it ?? > > > > > > Thanks again. > > > Navin > > > > > > On 2/27/07, Dennis Fisher <[EMAIL PROTECTED]> wrote: use R or Splus > > > > > > Excel would be a disaster - it is capped at ~ 64000 lines. > > > > > > Dennis Fisher MD P < (The "P Less Than" Company) Phone: 1-866- PLessThan (1-866-753-7784) Fax: 1-415-564-2220 www.PLessThan.com > > > > > > On Feb 27, 2007, at 1:39 PM, navin goyal wrote: > > > Hello everybody, > > > > > > I am trying to simulate PKPD data for 5000 patients, with each patient having around 100 time points. > > > > > > How could I create a data file for this simulation?? > > > Any help is appreciated. > > > Thanks > > > > > > Navin