RE: Welcome to the new small sample size world of NONMEM VI

From: Mark Sale - Next Level Solutions mark@nextlevelsolns.com Subject: RE: [NMusers] Welcome to the new small sample size world of NONMEM VI Date: Thu, 30 Nov 2006 17:10:24 -0700 Nick, You're right, the general expectation in the software world is for upward compatibility. The reason for the restriction on number of ids is the new option to sort the contributions to the OBJ before adding them, you have to store all the values in an array prior to sorting in this case an array of size 1000 by default. Whether or not to use sorting is also a option, (see page 4, #13). It was tested, at least a little. I think there would have been a way arround this if the SORT option isn't used (but not if SORT is used), but would have taken a lot more code. 1000 ids, I guess seemed generous. Wasn't in the beta because it was, I understand, one of the very last things added. Mark Sale MD Next Level Solutions, LLC www.NextLevelSolns.com _______________________________________________________