RE: ADAPT II with SAMPLE option

From: Lai-San Tham Date: April 19, 2006 technical Source: cognigencorp.com
From: "Tham Lai San, PHCV2" phcv2@nus.edu.sg Subject: RE: [NMusers] ADAPT II with SAMPLE option Date: Wed, 19 Apr 2006 08:06:41 +0800 Dear Nele, If you chose the option model input, then your drug is given like an infusion, and you will need to enter 2 event times. One for start of drug administration and one for stop whereby rate=0. This will tell ADAPT II the actual duration of infusion. If you consider SDinter and Sdslope as similar to assay error, then that will be similar to using the random unexplained variable from NONMEM. Regards, Lai San Tham
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Apr 19, 2006 Lai-San Tham RE: ADAPT II with SAMPLE option
Apr 19, 2006 Nele Mueller-Plock RE: ADAPT II with SAMPLE option