RE: Weighting in NONMEM
From: "GIRARD PASCAL" PASCAL.GIRARD@adm.univ-lyon1.fr
Subject: RE: [NMusers] Weighting in NONMEM
Date: Thu, 20 Apr 2006 08:12:57 +0200
Dear Pat,
Writing W=whatever in $ERROR has no action at all on NONMEM weightings. The purpose of writing
this is simply to compute individual weighted residuals (IWRES) which are not part of NONMEM output,
as opposed to population WRES provided by NONMEM. IWRES have to be computed according to individual
predictions F, evaluated according to POSTHOC ETAs which are evaluated either with POSTHOC option
if you use FO or are part of the computation with FOCE.
Best regards,
Pascal
Dr Pascal Girard
EA 3738, Ciblage Thrapeutique en Oncologie
Fac Mdecine Lyon-Sud, BP12
69921 OULLINS Cedex
France
Tel +33 (0)4 26 23 59 54 / Fax +33 (0)4 26 23 59 76