Effect of FOCE vs FOCE INTER on success of covariance step within a model with additive error
From: "Doshi, Sameer" sdoshi@amgen.com
Subject: [NMusers] Effect of FOCE vs FOCE INTER on success of covariance step within a model with additive error
Date: Thu, 9 Mar 2006 18:19:10 -0800
Hello,
I am trying to fit a model with additive error; Y=EFF+ERR(1) using FOCE
which converges successfully but ends with the following error:
0R MATRIX ALGORITHMICALLY NON-POSITIVE-SEMIDEFINITE
BUT NONSINGULAR
0COVARIANCE STEP ABORTED
I tried running the same model with FOCE INTER without making any other
changes to the control stream. When running the model with FOCE INTER, the
model converged (with the same results and objective function) and with a
successful covariance step.
Could the group please offer some insight as to why using FOCE INTER
resulted in a successful covarariance step when FOCE did not?
Thanks for your help,
Sameer
Sameer Doshi
Pharmacokinetics and Drug Metabolism, Amgen Inc.
(805) 447-6941